Rifaximin Cost: What You’ll Actually Pay

If you’ve been prescribed Rifaximin for IBS‑D, traveler's diarrhea, or liver disease, the first thing on your mind is likely the price tag. Rifaximin isn’t a cheap over‑the‑counter drug, but its cost can differ a lot depending on where you shop, whether you use a brand name or generic version, and what insurance coverage you have.

Why the Price Varies

Rifaximin is sold under the brand name Xifaxan and a few generic names. The brand version usually costs between $300 and $500 for a 14‑day supply, while generics can drop that to $150‑$250 for the same amount. Prices shift because manufacturers set different wholesale prices, and pharmacies add their own margins. Online pharmacies often have lower overhead, so they can pass savings on to you.

Insurance also plays a huge role. Some plans list Rifaximin as a specialty drug, which can mean higher co‑pays or prior‑authorization hurdles. If your plan treats it as a regular prescription, you might see a co‑pay of $20‑$50. Always check your plan’s formulary before you order.

How to Keep Costs Down

First, ask your doctor if a generic version is appropriate for your condition. Generics have the same active ingredient and are FDA‑approved, but they cost a fraction of the brand.

Second, shop around. Use price‑comparison tools or call a few local and online pharmacies to get quotes. Some online sites even let you upload your prescription and get a discount instantly.

Third, explore manufacturer coupons or patient‑assistance programs. The company that makes the brand drug often offers coupons that shave off $50‑$100 per month if you qualify.

Fourth, consider a 90‑day supply if your doctor says it’s safe. Buying a larger pack usually drops the per‑day cost by 10‑15%.

Lastly, look into pharmacy discount cards. They’re free, don’t require insurance, and can cut the price by up to 30% at many chains.

Remember, the cheapest option isn’t always the safest. Make sure any online pharmacy is licensed, requires a prescription, and has a pharmacist available for questions. If a deal sounds too good to be true, it probably is.

Bottom line: Rifaxinin cost can range from $150 to $500 for a two‑week course. By checking for generics, using coupons, comparing pharmacies, and confirming insurance coverage, you can bring that number down significantly. Talk to your doctor or pharmacist about these strategies, and you’ll still get the treatment you need without blowing your budget.