Tag: itraconazole
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Proton Pump Inhibitors and Antifungals: How They Interfere with Absorption and Effectiveness
Proton pump inhibitors can severely reduce absorption of some antifungals like itraconazole and ketoconazole, leading to treatment failure. Fluconazole is unaffected by stomach pH, while voriconazole requires monitoring. New research shows PPIs may also boost antifungal power against resistant fungi.