Dosage: 100mg Sildenafil + 10mg Vardenafil
Onset: 30-45 min
Duration: 4-6 hrs
Cost: $25-$30 (10 tablets)
Best for: Combination of speed and stamina
Dosage: 20mg
Onset: 30-60 min
Duration: Up to 36 hrs
Cost: $20-$25 (10 tablets)
Best for: Longest duration, weekend plans
Dosage: 100mg
Onset: 15-30 min
Duration: 6-12 hrs
Cost: $30-$35 (10 tablets)
Best for: Fastest onset, minimal visual side effects
Dosage: 50mg or 100mg
Onset: 30-60 min
Duration: 4-6 hrs
Cost: $10-$15 (10 tablets)
Best for: Most affordable, tried-and-true
All PDE5 inhibitors share similar contraindications including heart issues, certain medications, and severe liver problems. Always consult with a healthcare provider before starting any new medication.
When it comes to treating erectile dysfunction, Silvitra is a combination tablet that merges two popular phosphodiesterase‑5 inhibitors-Sildenafil and Vardenafil-into a single dose. The idea is to give users the quick kick‑off of Sildenafil with the slightly longer window of Vardenafil, all while keeping the pill count low.
Silvitra is marketed as a 100mg/10mg blend (100mg Sildenafil plus 10mg Vardenafil). It is taken about an hour before sexual activity and can stay effective for up to six hours, depending on individual metabolism. The product is sold in several countries under prescription‑only status and is often priced higher than single‑ingredient generics because of the dual formulation.
Both Sildenafil and Vardenafil belong to the Phosphodiesterase type 5 inhibitors (PDE5i). They block the PDE5 enzyme, which normally breaks down cyclic GMP-a molecule that relaxes smooth muscle in the penis. By inhibiting PDE5, blood flow improves, allowing an erection when sexual stimulation occurs. The slight differences in how each drug binds to PDE5 give the combination a broader therapeutic window: Sildenafil kicks in fast (about 30‑45 minutes), while Vardenafil adds a bit more stamina.
If you’re weighing Silvitra against other options, here’s a quick list of the most common competitors:
All PDE5 inhibitors share a core set of possible side effects: headache, flushing, nasal congestion, indigestion, and visual disturbances. The intensity often depends on dose and personal sensitivity. Herbal options tend to cause gastrointestinal upset or interact with blood‑pressure meds, but they rarely produce the classic PDE5‑related visual changes.
Product | Active ingredient(s) | Typical dose | Onset | Duration | Prescription? | Average cost (USD) |
---|---|---|---|---|---|---|
Silvitra | Sildenafil+Vardenafil | 100mg+10mg | 30‑45min | 4‑6hr | Yes | $25‑$30 (10 tablets) |
Tadalafil | Tadalafil | 20mg | 30‑60min | Up to 36hr | Yes | $20‑$25 (10 tablets) |
Avanafil | Avanafil | 100mg | 15‑30min | 6‑12hr | Yes | $30‑$35 (10 tablets) |
Generic Sildenafil | Sildenafil | 50mgor100mg | 30‑60min | 4‑6hr | Yes | $10‑$15 (10 tablets) |
Generic Vardenafil | Vardenafil | 10mg | 30‑60min | 4‑5hr | Yes | $12‑$18 (10 tablets) |
L‑arginine (herbal) | L‑arginine | 500‑1000mg daily | - | - | No | $5‑$10 (30 capsules) |
All pills in this class share a core blacklist:
Drug interactions worth noting include:
Always run a quick medication check with your pharmacist, especially if you’re on blood‑pressure, anti‑depressant, or HIV meds.
In most regions, Silvitra requires a written prescription from a qualified clinician. Tele‑health platforms that specialise in men’s health now offer rapid video consultations, often delivering the medication within 1‑2 business days. For travelers, a local doctor can write a short‑term script, but be prepared to show your medical history.
A small amount of alcohol (one‑two drinks) usually isn’t a problem, but heavy drinking can amplify the drop in blood pressure that PDE5 inhibitors cause. It’s safest to limit intake and give the medication at least an hour before drinking.
Clinical data are limited, but many users report a slightly stronger response because Vardenafil adds a secondary pathway of action. The improvement isn’t dramatic; for most men, a well‑timed Sildenafil dose works just as well.
Seek emergency medical care immediately. Prolonged erections (priapism) can damage penile tissue. This risk is rare but higher if you combine PDE5 inhibitors with other vasodilators.
No OTC product matches the proven effectiveness of prescription PDE5 inhibitors. Supplements like L‑arginine may help a bit, but they lack robust clinical backing and usually require high daily doses.
Diabetes itself isn’t a contraindication, but the condition can affect nerve and blood‑vessel function, making ED more common. Most men with diabetes can safely use Silvitra after a doctor confirms there are no heart‑related issues.